Category
Atorvastatin
CAS Number
357164-38-6
Molecular Formula
C66H70CaF2N4O11
Molecular Weight
1173.4 g/mol
Synonym

Atorvastatin Calcium Salt Hydrate; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-
dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt, hydrate (2:1:?), (βR,δR); 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), hydrate, (βR,δR); calcium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate Hydrate;calcium;bis((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate);hydrate;

Keywords
Impurities
Metabolites.
Pharmaceutical Standards
Intermediates
Fine Chemicals
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Atorvastatin Calcium Hydrate (CAS No: 357164-38-6) is the pharmaceutically active form of atorvastatin, supplied as a high-purity calcium salt. With a molecular formula of C₆₆H₇₀CaF₂N₄O₁₁ and a molecular weight of 1173.4 g/mol, it is widely used as the API in cholesterol-lowering therapy and cardiovascular disease management. Its high chemical and stereochemical purity ensures potent HMG-CoA reductase inhibition, making it a critical compound for pharmaceutical manufacturing and formulation development.

This API is extensively employed in process development, analytical method validation, and quality control. Techniques such as HPLC, LC-MS/MS, and chiral chromatography are used for precise impurity profiling, quantification, and stereochemical verification. Monitoring Atorvastatin Calcium Hydrate is essential to maintain compliance with USP, EP, and ICH standards and to ensure consistent API quality in bulk manufacturing and dosage form production.

Manasa Life Sciences, based in Hyderabad, supplies certified, traceable, and high-purity Atorvastatin Calcium Hydrate reference standards to pharmaceutical manufacturers and research institutions worldwide. With full documentation and adherence to Good Documentation Practices (GDP), the company supports API manufacturing, regulatory compliance, and analytical method development across Asia, Europe, Africa, the GCC, and UAE, ensuring reliable supply and quality assurance for global pharmaceutical markets.