Category
Aprepitant
CAS Number
171338-33-3
Alternate CAS Number
874460-46-5(HCl Salt)
Molecular Formula
C₂₀H₁₉F₆NO₂
Molecular Weight
419.36 g/mol
Synonym

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholine; Aprepitant Desfluoro Spot-1

Keywords
Impurities
Metabolites.
Pharmaceutical Standards
Intermediates
Fine Chemicals
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Aprepitant Impurity 2 is a process-related byproduct of the anti-nausea drug aprepitant. Chemically, it is (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine and is used as a reference standard in analytical testing and quality control to identify and quantify this impurity in the drug during manufacturing.