Category
Fluticasone
CAS Number
Fluticasone Furoate- 397864-44-7; IMP-E - 398454-97-2; IMP-F- NA: IMP-G -785806-96-4
Molecular Formula
Fluticasone Furoate- C27H29F3O6S; IMP-E - C27H30F2O6S; IMP-F- C29H34F2O7: IMP-G- C27H29ClF2O6S
Molecular Weight
Fluticasone Furoate- 538.58 g/mol; IMP-E- 520.59 g/mol; IMP-F- 532.57 g/mol: IMP-G- 555.03 g/mol
Synonym

Fluticasone Furoate – (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate 

Fluticasone Furoate EP IMP E- (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ; 9-Fluoro-17-[[(fluoromethyl)sulfanyl]carbonyl]-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl furan-2-carboxylate;

Fluticasone Furoate EP IMP F (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-17-(isopropoxycarbonyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ; Propan-2-yl 6alpha,9-difluoro-17alpha-[(furan-2-carbonyl)oxy]-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carboxylate;

Fluticasone Furoate EP IMP G - 9-Chloro-6alpha-fluoro-17beta-(((fluoromethyl)sulfanyl)carbonyl)-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl furan-2-carboxylate ; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-6-fluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta(a)phenanthren-17-yl furan-2-carboxylate

 

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Fluticasone furoate CRS is used to assess system suitability parameters such as resolution, repeatability, and peak symmetry in chromatographic analysis. It ensures reliable performance of analytical systems for fluticasone furoate formulations.