Category
Codeine
CAS Number
Codeine STD- 76-57-3: IMP-A- 2859-16-7: IMP-B- 57-27-2: IMP-C- 121395-47-9: IMP-D- 2585669-81-2: IMP-E- 1777-89-5: IMP-F- 4829-46-3: IMP-G- 115-37-7: IMP-H- 467-15-2: IMP-I- 467-13-0
Alternate CAS Number
Codeine STD- 6059-47-8(Monohydrate salt): IMP-B- 52-26-6 (HCl salt): IMP-H- 14648-14-7 (HCl salt)
Molecular Formula
Codeine STD- C₁₈H₂₁NO₃: IMP-A- C₁₉H₂₃NO₃: IMP-B- C₁₇H₁₉NO₃: IMP-C- C₃₆H₄₀N₂O₆: IMP-D- C₃₅H₃₈N₂O₆: IMP-E- C₁₈H₂₁NO₄: IMP-F- C₁₈H₂₁NO₄: IMP-G- C₁₉H₂₁NO₃: IMP-H- C₁₇H₁₉NO₃: IMP-I- C₁₈H₁₉NO₃
Molecular Weight
Codeine STD- 299.4: IMP-A- 313.4: IMP-B- 285.3: IMP-C- 596.7: IMP-D- 582.7: IMP-E- 315.4: IMP-F- 315.4: IMP-G- 311.4: IMP-H- 285.3: IMP-I- 297.4
Synonym

Codeine STD- (5α,6α)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol; (4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol

Codeine EP Impurity A- (4R,4aR,7S,7aR,12bS)-7,9-dimethoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline; 4,5α-epoxy-3,6α-dimethoxy-17-methyl-7,8-didehydromorphinan (as per EP)

Codeine EP Impurity B- 4,5α-epoxy-17-methyl-7,8-didehydromorphinan-3,6α-diol (as per EP) ; 7,8-Didehydro-4,5α-epoxy-17-methylmorphinan-3,6α-diol (as per USP); Morphine (EP & USP)

Codeine EP Impurity C- 4,5α:4′,5′α-diepoxy-3,3′-dimethoxy-17,17′-dimethyl-7,7′,8,8′-tetradehydro-2,2′-bimorphinan-6α,6′α-diol (as per EP) ; 7,7′,8,8′-Tetradehydro-4,5α:4′,5′α-diepoxy-3,3′-dimethoxy-17,17′-dimethyl-2,2′-bimorphinanyl-6α,6′α-diol (as per USP)

Codeine EP Impurity D- 4,5α-epoxy-2-[(4,5α-epoxy-6α-hydroxy-17-methyl-7,8-didehydromorphinan-3-yl)oxy]-3-methoxy-17-methyl-7,8-didehydromorphinan-6α-ol (as per EP); 3-O-(Codein-2-yl)morphine (EP)

Codeine EP Impurity E- 4,5α-epoxy-3-methoxy-17-methyl-7,8-didehydromorphinan-6α,10ξ-diol (as per EP) ; 7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α, 10-diol (as per USP); 10-Hydroxycodeine (USP)

Codeine EP Impurity F- 4,5α-epoxy-3-methoxy-17-methyl-7,8-didehydromorphinan-6α,14-diol (as per EP) ; 7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α, 14-diol (as per USP); 14-Hydroxycodeine (USP)

Codeine EP Impurity G- 4,5α-epoxy-3,6-dimethoxy-17-methyl-6,7,8,14-tetradehydromorphinan (as per EP) ; 6,7,8,14-Tetradehydro-4,5α-epoxy-3,6-dimethoxy-17-methylmorphinan (as per USP); Thebaine (EP & USP) ; Oxycodone EP Impurity F

Codeine EP Impurity H- 4,5α-epoxy-3-methoxy-7,8-didehydromorphinan-6α-ol (as per EP) ; 7,8-Didehydro-4,5α-epoxy-3-methoxymorphinan-6α-ol (as per USP); Norcodeine (EP & USP)

Codeine EP Impurity I- 4,5α-Epoxy-3-methoxy-17-methyl-7,8-didehydromorphinan-6-one (as per EP) ; 7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-one (as per USP); Codeinone (EP & USP)

Keywords
Pharmaceutical Standards
Impurities
Impurities manufacturer and Suppliers in Hyderabad india
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Codeine for System Suitability CRS (Chemical Reference Standard) is a high-purity analytical reference standard used in pharmaceutical quality control and analytical method validation. It is widely applied in HPLC and GC analysis for system suitability testing, ensuring accuracy, precision, resolution, and reproducibility during analysis of Codeine and related compounds. Manasa Life Sciences is a manufacturer and supplier of Codeine for System Suitability CRS, providing certified reference standards with CoA and MSDS, compliant with ICH guidelines, USP/EP, and regulatory requirements for pharmaceutical R&D, CROs, and QC laboratories.