Category
Chlortetracycline
CAS Number
Chlortetracycline STD - 57-62-5 ; Tetracycline - 60-54-8; IMP - A - 14297-93-9 ; IMP - B - 127-33-3 ; IMP - D-79-85-6 ;IMP - E- 14206-59-8 ;IMP - G - 514-53-4; IMP – H - 7301-38-4; IMP - J - 13803-65-1 ; IMP – K - 81163-11-3 ; IMP – L - 4497-08-9;
Molecular Formula
STD - C₂₂H₂₃ClN₂O₈ ; Tetracycline - C₂₂H₂₄N₂O₈ ;IMP - A -C₂₂H₂₃ClN₂O₈;IMP-B-C₂₁H₂₁ClN₂O₈; IMP -D-C₂₂H₂₄N₂O₈ ;IMP - E- C₂₁H₂₁ClN₂O₈ ;IMP - G - C₂₂H₂₃ClN₂O₈ ; IMP - H - C₂₃H₂₄ClNO₈;IMP - J - C₂₂H₂₃ClN₂O₇ ; IMP - K - C₂₂H₂₁ClN₂O₇;IMP -L- C₂₂H₂₁ClN₂O₇ ;
Molecular Weight
Chlortetracycline STD - 478.88; Tetracycline - 444.44 ; IMP - A - 478.9 ; IMP - B - 464.9 ; IMP - D- ;IMP - E- 464.9 g/mol ;IMP - G - 478.88 ; IMP - H - 477.9; IMP - J - 462.88 ; IMP - K - 460.87 ; IMP – L- 460.9 - ;
Synonym

Chlortetracycline - 7-Chlortetracycline; A-Mycin; Acronize; Aureomycin; Aureomykoin; Chlortetracyclin; Chrysomykine; Uromycin; 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α,4aα,5aα,6β,12aα)]-; (4S,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide;

Tetracycline  -  (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1, 11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

Chlortetracycline-EP-IMP-A-(4R,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)- 3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (4-epichlortetracycline), 4-epi-Chlortetracycline;

Chlortetracycline-EP-IMP-B-

(4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (demeclocycline),

Chlortetracycline-EP-IMP-D- 

(4R,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12apentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide (4-epitetracycline),

Chlortetracycline-EP-IMP- E -  

(4R,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (4-epidemethylchlortetracycline)

Chlortetracycline-EP-IMP-G-

(4S,4aS,6S,8aS)-6-[(1R)-7-chloro-4-hydroxy-1-methyl-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-4-(dimethylamino)-3,8a-dihydroxy-1,8-dioxo1,4,4a,5,6,7,8,8a-octahydronaphthalene-2-carboxamide (isochlortetracycline) ;

Chlortetracycline-EP-IMP-H-

(4S,4aS,5aS,6S,12aS)-2-acetyl-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl4a,5a,6,12a-tetrahydrotetracene-1,11(4H,5H)-dione (2-acetyl-2-decarboxamidochlortetracycline)

Chlortetracycline-EP-IMP-J-(4S,4aS,12aS)-4-(dimethylamino)-3,10,12,12atetrahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,11,12ahexahydrotetracene-2-carboxamide (anhydrotetracycline)

Chlortetracycline EP – IMP- k –(4R,4aS,12aS)-7-chloro-4-(dimethylamino)- 3,10,12,12a-tetrahydroxy-6-methyl-1,11-dioxo1,4,4a,5,11,12a-hexahydrotetracene-2-carboxamide (4-epianhydrochlortetracycline),

Chlortetracycline EP - IMP - L -(4S,4aS,12aS)-7-chloro-4-(dimethylamino)- 3,10,12,12a-tetrahydroxy-6-methyl-1,11-dioxo1,4,4a,5,11,12a-hexahydrotetracene-2-carboxamide (anhydrochlortetracycline).

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Chlortetracycline system suitability CRS (Chemical Reference Substance) is used as a standard to verify the performance and reliability of analytical methods, especially in chromatographic systems. It helps ensure accuracy, precision, and proper system functioning during the analysis of chlortetracycline in pharmaceutical preparations.