Atazanavir is an antiretroviral drug used in the treatment of HIV infection and belongs to the protease inhibitor class of medications. It works by inhibiting the HIV protease enzyme, which is necessary for viral replication, thereby reducing the amount of virus in the body and helping to improve immune function. Atazanavir is usually taken once daily as part of combination antiretroviral therapy and is often boosted with ritonavir or cobicistat to enhance its effectiveness. Compared to other protease inhibitors, it is associated with fewer lipid abnormalities, making it a suitable option for some patients. However, it may cause side effects such as elevated bilirubin levels, which can lead to yellowing of the skin or eyes, and should be used under proper medical supervision.