Furosemide is a potent loop diuretic used to treat edema due to heart failure, liver disease, and kidney disorders, as well as hypertension, by inhibiting sodium and chloride reabsorption in the loop of Henle to increase urine output. Developed in the early 1960s and introduced by Hoechst Pharmaceuticals, it was approved in 1966 and quickly became a major advance in diuretic therapy, remaining widely used today for its rapid action, effectiveness, and affordability.
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